IL-6 Test Kit (Dry Fluorescence Immunoassay)
Product Description
1. DSC utilizes an advanced methodology called Time-resolved Fluorescence Immunoassay (TRFIA) Method. TRFIA is super-sensitive detection technique characterized by specific fluorescence of rare earth ions. It is not only highly sensitive, but also overcomes the instability of enzyme marker and is the best choice for immunological detection. The high fluorescence intensity and long life of labeled ionic chelates are beneficial to eliminate the influence of fluorescent substances in samples and environment on the test results.
2. Analyzer Introduction: Analyzer uses the advanced method of Time-resolved Fluorescence Immunoassay (TRFIA), for the in-vitro quantitative detection of bio-markers for Diabetes Mellitus, Inflammation, Cardiovascular Diseases, Hormone, Gastric Diseases, Renal Diseases, Tumor, etc.
3. Application: Laboratory, ER, Cardiology, ICU, Respiratory, Pediatrics, etc.
Interleukin-6(IL-6)is a cytokine that belongs to the class of interleukins. It is produced by fifibroblasts, monocytes/macrophages, T lymphocytes, B lymphocytes, epithelial cells, keratinocytes, and various tumor cells.
IL-6 plays a critical role in regulating the acute phase response, hematopoiesis, inflflam mation, metabolic control, liver regeneration, bone metabolism and cancer progression.
Higher outcomes may be multiple myeloma, psoriatic arthritis, psoriasis, and multiple myelomatosis nephropathy.
IL-6 Signaling Pathway
IL-6 signals is initiated by binding to its receptor named IL-6R. IL-6R protein has two forms in cells, one is membrane-bound form, and another is soluble (aIL-6R) form. If cells do not express IL-6R, they can be stimulated by a complex formed by IL-6 and a sIL-6R. Releasing the IL-6R protein presenting cells, which presents a gp130-responsive response to IL-6 cytokines. In addition, IL-6 responsive cells are very sensitive to IL -6R.
The function of IL-6 in autoimmune and chronic inflflammatory diseases
Steps of Operation
Interpretation of Result
IL-6 |
Measuring Range |
4.8pg/mL-2000pg/mL |
Cut-Offff Value |
10pg/mL |